How Hypertension Causes Kidney Failure

How Hypertension Causes Kidney Failure


How Hypertension Causes Kidney Failure

High blood pressure, or hypertension, can harm the kidneys and possibly result in kidney failure. By filtering waste materials and extra fluid from the blood, managing electrolyte balance, and producing hormones that regulate blood pressure, the kidneys play a critical role in preserving the body’s overall health. The delicate blood vessels inside the kidneys can sustain excessive force if blood pressure is kept consistently high. Numerous negative consequences may result from this increased pressure.

To effectively carry out their filtration function, the kidneys depend on a network of tiny blood vessels, including the glomerular capillaries. These blood vessels may become thickened and narrowed (a condition known as arteriosclerosis), which will reduce blood flow to the kidneys. Persistently high blood pressure can also harm these blood vessels. The kidneys’ capacity to filter waste products may be compromised by the reduced blood flow, which could result in an accumulation of toxins in the bloodstream.

Glomeruli, the minuscule filtering units found inside the kidneys, scar and harden over time. This condition is referred to as glomerulosclerosis.
Hypertension can exacerbate the pressure on the glomerular capillaries, causing these tissues to become damaged and lose their ability to filter blood. Proteinuria (excess protein in the urine) can result from damaged glomeruli scarring over time, which reduces their capacity to filter waste products. Glomerulosclerosis can lead to chronic kidney disease and ultimately kidney failure if it is not treated.

Renin, angiotensin, and aldosterone are just a few of the blood pressure-regulating hormones that are produced by the kidneys. The regular balance of these hormones may be thrown off by persistently high blood pressure. For instance, the kidneys might secrete too much renin, which sets off a chain of events that leads to more fluid retention and increased vasoconstriction (the narrowing of blood vessels) and raises blood pressure even more. These hormonal imbalances have the potential to keep kidney damage and hypertension from stopping.

Kidney blood flow can be decreased by hypertension by damaging the arteries that carry blood to the kidneys. The kidneys’ function is hampered because of the reduced blood flow, which deprives them of sufficient oxygen and vital nutrients. Aside from that, decreased blood flow causes the kidneys to respond in a compensatory manner, releasing more hormones into the bloodstream that can raise blood pressure even higher.

Kidney stones may be more likely to develop in people with chronic hypertension. High blood pressure can alter the ratio of salts and minerals in the urine, causing them to build up and crystallize. If left untreated, these crystals may develop over time into kidney stones, which can block the urinary tract and harm the kidneys. It’s crucial to understand that hypertension is a complex condition with many underlying causes. While kidney failure is one possible outcome of uncontrolled high blood pressure, it is not the only one. Additional side effects from hypertension include heart disease, stroke, and organ damage.

Effective blood pressure management is essential to reduce the risk of kidney failure caused by hypertension. A healthy diet that is low in sodium and high in fruits, vegetables, and whole grains, regular exercise, managing your weight, drinking less alcohol, and reducing stress are all lifestyle changes that can help you control your blood pressure. To effectively control blood pressure, medical professionals may also prescribe drugs like antihypertensive medications.


Content

0.38 -> hypertension or high blood pressure can
3.3 -> have detrimental effects on the kidneys
5.46 -> potentially leading to kidney failure
8.76 -> the kidneys play a vital role in
11.28 -> maintaining the body's overall health by
13.86 -> filtering waste products and excess
16.139 -> fluids from the blood regulating
18.359 -> electrolyte balance and producing
20.76 -> hormones that control blood pressure
23.939 -> when blood pressure remains consistently
26.58 -> elevated it can exert excessive force on
29.64 -> the delicate blood vessels within the
31.74 -> kidneys
33.12 -> this increased pressure can cause
35.399 -> several damaging effects
37.86 -> 1. damage to the renal blood vessels
41.82 -> the kidneys rely on a network of small
44.34 -> blood vessels including the glomerular
46.739 -> capillaries to perform their filtration
49.26 -> function effectively
51.539 -> persistent high blood pressure can
53.94 -> damage these blood vessels leading to
56.219 -> thickening and narrowing a condition
58.32 -> called arteriosclerosis and reducing the
61.559 -> blood flow to the kidneys
64.26 -> the impaired blood flow can compromise
66.96 -> the kidney's ability to filter waste
69.24 -> products leading to the accumulation of
71.7 -> toxins in the bloodstream
74.159 -> 2. glomerulosclerosis
78.2 -> glomerulosclerosis refers to the
80.22 -> scarring and hardening of the glomeruli
82.439 -> which are the tiny filtering units
84.6 -> within the kidneys
86.7 -> The increased pressure on the glomerular
88.92 -> capillaries caused by hypertension can
91.92 -> damage these structures impairing their
94.259 -> filtration function
96.36 -> over time the damaged glomeruli may
99.42 -> become scarred decreasing their ability
101.7 -> to effectively filter waste products and
104.579 -> leading to proteinuria the presence of
106.86 -> excess protein in the urine
109.439 -> if left uncontrolled
111.68 -> glomerulosclerosis can progress to
113.88 -> chronic kidney disease and eventually
115.979 -> kidney failure
118.14 -> three disruption of hormonal regulation
121.92 -> the kidneys produce several hormones
124.079 -> involved in regulating blood pressure
126.24 -> including renin Angiotensin and
129.36 -> aldosterone
131.099 -> when blood pressure is consistently High
133.739 -> the normal balance of these hormones can
136.379 -> be disrupted
138.06 -> for instance the kidneys may release
140.52 -> excessive amounts of renin which
142.68 -> triggers a Cascade of reactions that
145.02 -> result in increased vasoconstriction
147.26 -> narrowing of blood vessels and fluid
150.18 -> retention further elevating blood
152.34 -> pressure
153.78 -> these hormonal imbalances can perpetuate
156.72 -> a cycle of hypertension and kidney
158.879 -> damage
160.44 -> 4. reduced blood flow to the kidneys
164.599 -> hypertension can also damage the
167.04 -> arteries that supplied blood to the
169.14 -> kidneys reducing the overall blood flow
172.86 -> the diminished blood flow deprives the
175.56 -> kidneys of adequate oxygen and essential
178.14 -> nutrients impairing their function
181.26 -> additionally reduced blood flow triggers
184.379 -> a compensatory response in the kidneys
186.78 -> leading to the release of additional
188.819 -> hormones that can further increase blood
191.22 -> pressure
192.72 -> 5 formation of kidney stones
196.2 -> chronic hypertension can increase the
198.78 -> risk of developing kidney stones
201.84 -> high blood pressure can affect the
204.18 -> balance of salts and minerals in the
206.459 -> urine leading to their accumulation and
209.04 -> the formation of crystals
211.379 -> these crystals can gradually grow into
214.019 -> kidney stones which can obstruct the
216.42 -> urinary tract and cause kidney damage if
219.36 -> not adequately addressed
221.76 -> it's important to recognize that
223.68 -> hypertension is a complex condition with
226.26 -> multiple contributing factors
229.019 -> while kidney failure is a potential
231.42 -> consequence of uncontrolled high blood
233.459 -> pressure it is not the sole outcome
236.84 -> hypertension can also lead to other
239.159 -> complications such as heart disease
241.62 -> stroke and damage to other organs
245.459 -> to minimize the risk of kidney failure
247.86 -> associated with hypertension it is
250.5 -> crucial to manage blood pressure
252.12 -> effectively
253.86 -> lifestyle modifications including
256.56 -> adopting a healthy diet low in sodium
259.199 -> and rich in fruits vegetables and whole
262.199 -> grains regular exercise weight
264.84 -> management limited alcohol consumption
267.6 -> and stress reduction can all contribute
270.54 -> to blood pressure control
272.9 -> medications such as antihypertensive
275.94 -> drugs may also be prescribed by Health
278.46 -> Care Professionals to help manage blood
280.8 -> pressure effectively
282.78 -> if you have concerns about your blood
284.88 -> pressure or Kidney Health it is
287.1 -> essential to consult with a health care
288.96 -> professional who can provide
290.639 -> personalized advice conduct appropriate
293.34 -> screenings and recommend the most
295.5 -> suitable management strategies for your
298.02 -> specific situation

Source: https://www.youtube.com/watch?v=U8G9tTa0U-8