MedTap: Why mineralocorticoid receptor antagonists in heart failure with reduced ejection fraction?
MedTap: Why mineralocorticoid receptor antagonists in heart failure with reduced ejection fraction?
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5.84 -> Mineralocorticoid receptor antagonists
(known as MRAs) are often prescribed in patients
11.84 -> with heart failure with reduced ejection fraction.
These medications are spironolactone and eplerenone.
21.84 -> They're started in patients who
still have heart failure symptoms
25.6 -> despite being on a beta blocker
and an ACE-I inhibitor or equivalent.
32.08 -> MRAs work with your kidneys to prevent the
build-up of salt and water in your blood.
38.32 -> This allows your heart to pump blood around your body more easily.
You may not always be able to tell
46 -> that your MRA is working but you should hopefully
start to notice an improvement in your symptoms
51.36 -> after a few weeks. MRAs are key medications.
They help you to reduce the need to be hospitalised,
60.72 -> they make you feel better
and they make you live longer.
65.04 -> MRAs are usually continued long
term to help support your heart.
Source: https://www.youtube.com/watch?v=LwoqZWQKDHI