Friday Favorites: Benefits of Flaxseeds for Inflammation

Friday Favorites: Benefits of Flaxseeds for Inflammation


Friday Favorites: Benefits of Flaxseeds for Inflammation

Elevated levels of pro-inflammatory, aging-associated oxylipins can be normalized by eating ground flaxseed.

Here’s the video I did on Flax Seeds for Hypertension (https://nutritionfacts.org/video/Flax

What about flax and cancer? See:
• Flaxseeds \u0026 Breast Cancer Survival: Clinical Evidence (https://nutritionfacts.org/video/flax…)
• Can Flax Seeds Help Prevent Breast Cancer? (https://nutritionfacts.org/video/Can-…)
• Flaxseed vs. Prostate Cancer (https://nutritionfacts.org/video/flax…)
• Flaxseeds \u0026 Breast Cancer Prevention (https://nutritionfacts.org/video/flax…)

I also have one on diabetes: Flaxseeds vs. Diabetes (https://nutritionfacts.org/video/flax…)

And weight loss: Benefits of Flaxseed Meal for Weight Loss (http://nutritionfacts.org/video/benef…)

But what about the cyanide content of flax? I answered that in
How Well Does Cooking Destroy the Cyanide in Flaxseeds? (http://nutritionfacts.org/video/how-w…) and Should We Be Concerned About the Cyanide from Flaxseed? (http://nutritionfacts.org/video/shoul…)

What else can help fight inflammation? Check out:
• Inhibiting Platelet Aggregation with Berries (https://nutritionfacts.org/video/inhi…)
• Turmeric Curcumin and Osteoarthritis (https://nutritionfacts.org/video/turm…)
• Turmeric Curcumin and Rheumatoid Arthritis (https://nutritionfacts.org/video/turm…)
• Which Spices Fight Inflammation? (https://nutritionfacts.org/video/whic…)
• Dietary Treatment for Painful Menstrual Periods (https://nutritionfacts.org/video/diet…)
• Benefits of Turmeric Curcumin for Inflammatory Orbital Pseudotumor (https://nutritionfacts.org/video/bene…)
• The Effects of Avocados and Red Wine on Meal-Induced Inflammation (https://nutritionfacts.org/video/effe…)

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Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/video/frid… You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics.

Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution!
-Michael Greger, MD FACLM

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Content

0.71 -> [Music]
2.159 -> foreign
3.91 -> [Music]
11.599 -> the potent anti-hypertensive effect of
14.58 -> dietary flaxseed in hypertensive
16.98 -> patients this was a double randomized
20.34 -> placebo-controlled trial where they
21.96 -> disguised ground flaxseed and baked
24.119 -> goods versus like flax free Placebo
27 -> muffins and got an extraordinary drop in
29.58 -> high blood pressures as you can imagine
31.679 -> the flaxseed industry was overjoyed
34.8 -> praising the impressive findings as was
37.2 -> I after all high blood pressure is the
39.899 -> single largest risk factor for death on
42.78 -> the planet Earth
44.219 -> yes we give people medications lots and
48.3 -> lots of medications but most people
51 -> don't take them as in nine out of 10
53.7 -> people take less than 80 percent of the
55.559 -> prescribed blood pressure pills just
57.12 -> eight percent
59.28 -> it's not difficult to understand why
61.559 -> patients are asked to follow An
63.719 -> Inconvenient potentially costly regimen
65.88 -> which will likely have detrimental
68.22 -> effect on their health related quality
69.78 -> of life to treat it mostly asymptomatic
72.96 -> condition so they may feel worse instead
76.26 -> of better due to the side effects the
78.6 -> answer then is to give them more drugs
81.18 -> too counteract the effects of the first
82.619 -> drugs like giving men Viagra to counter
85.08 -> the erectile dysfunction caused by their
87.54 -> blood pressure pills how about using a
90.06 -> dietary strategy instead especially if
92.759 -> it can just be as effective and indeed
95.22 -> the drop in blood pressures they got in
97.14 -> the flaxseed study was greater than the
99.72 -> average decreased observed with the
101.64 -> standard dose of antihypertensive drugs
103.74 -> and flax seeds are cheaper too compared
106.799 -> to even single medications than most
108.54 -> patients are on multiple drugs and has
112.14 -> good side effects beyond their
113.72 -> anti-hypertensive actions but not all
116.46 -> good taking tablespoons of flaxseed a
118.799 -> day is a lot of fiber for people who've
120.899 -> been you know living off of
122.1 -> cheeseburgers and milkshakes their whole
123.479 -> lives it can take a little while for
124.92 -> your gut bacteria to adjust to the new
128.039 -> Bounty so people who start out with low
130.619 -> fiber diets may want to take it slow at
133.68 -> first
135 -> not all Studies have shown significant
137.4 -> blood pressure lowering effects there
138.959 -> have been over a dozen trials by now
140.7 -> involving more than a thousand subjects
142.56 -> and though yes you know put them all
143.879 -> together and overall there were
145.319 -> significant reductions in both systoc
147.599 -> and diastolic blood pressures the upper
149.28 -> and lower numbers following
150.78 -> supplementation with various flaxseed
152.34 -> products none were as dramatic as that
154.86 -> six-month trial the longer trials tended
158.04 -> to show better results and some of the
160.14 -> trials just used flaxseed oil or some
162.54 -> kind of flax seed extract and the
164.76 -> thought is that the whole is greater
166.5 -> than the sum of its parts
168.9 -> the components of interest within
170.94 -> flaxseed the Omega-3s the the
172.8 -> cancer-fighting lignans all the soluble
175.2 -> fiber and plant proteins all contribute
177.239 -> toward the blood pressure reduction okay
180 -> but how why right what's the mechanism
183.84 -> some common blood pressure medications
185.94 -> like Norvasc or Procardia work by
188.459 -> reducing the ability of the heart to
190.98 -> contract or slowing the heart down and
193.2 -> so it's possible that's how flax seeds
195.48 -> work too but no dietary flaxseed reduces
198.659 -> blood pressure without cardiac
200.22 -> involvement but rather through changes
202.58 -> in plasma oxylipins
206.42 -> what are oxy lipids oxy lipins a group
209.94 -> of fatty acid metabolites involved in
212.099 -> inflammation and as a result have been
213.9 -> implicated in many pro-inflammatory
216.06 -> conditions including cardiovascular
217.739 -> disease and aging the best characterized
220.44 -> oxy lipids in relation to cardiovascular
222.599 -> disease are derived from the long-chain
225.06 -> omega-6 fatty acids known as arachidonic
228.239 -> Acid found pre-formed in animal products
230.34 -> particularly chicken and eggs and can be
233.459 -> made inside the body from junky omega-6
235.68 -> Rich oil such as cottonseed oil but
238.14 -> elevated levels of pro-inflammatory oxy
240.299 -> lipids in older subjects are normalized
242.819 -> by flax seed consumption see that's how
246 -> we think flaxseed consumption reduces
247.799 -> blood pressure in patients with
248.819 -> hypertension by inhibiting the enzyme
251.459 -> that makes these pro-inflammatory
253.08 -> oxylipins also
255.78 -> spare you from the acronym overload but
258.359 -> basically eating flax seeds inhibits the
260.459 -> activity the enzyme that makes these
262.32 -> pro-inflammatory oxylipins called
264.02 -> leukotoxin dinos which in turn May lower
267.24 -> blood pressure identifying the molecular
269.58 -> mechanisms adds confidence to the
271.56 -> antihypertensive actions of dietary
273.54 -> flaxseed but that's not all oxy lipids
276.36 -> do oxy lipens may play a role in the
278.639 -> aging process but we may be able to
280.8 -> beneficially disrupt these biological
283.139 -> changes associated with inflammation and
284.88 -> aging with nutritional intervention like
287.82 -> flaxseed older adults around age 50 have
291.66 -> higher levels of these arachidonic acid
293.82 -> derived oxy-lipens compared to younger
296.58 -> adults around age 20. and these elevated
299.34 -> concentrations are pro-inflammatory
301.44 -> oxalip into the older age group may help
303.36 -> explain the higher levels of
304.86 -> inflammation in older versus younger
307.199 -> individuals I mean as we get older right
309.72 -> we're more likely to be stricken with
311.699 -> inflammatory conditions like arthritis
313.5 -> so this elevation of pro-inflammatory
316.08 -> oxy lipids May predispose individuals to
318.479 -> chronic disease conditions
320.699 -> but what if you took these older adults
322.74 -> and gave them muffins ground flaxseed
326.639 -> containing muffins four weeks later
329.699 -> their levels dropped to here right
333.18 -> down to like 20 year old levels
335.58 -> demonstrating that a potential
337.139 -> therapeutic strategy to correct the
338.94 -> deleterious pro-inflammatory oxylipin
341.16 -> profile is via dietary supplementation
343.74 -> with flax
348.47 -> [Music]
354.539 -> thank you

Source: https://www.youtube.com/watch?v=bedVW65m0No