A rapid blood test for stroke
A rapid blood test for stroke
UC Riverside Ph.D. candidate Jessica Noll gives a three-minute pitch at the 2018 Grad Slam on a simple product to diagnose a stroke in a matter of minutes.
https://gradslam.universityofcaliforn…
Content
1.92 -> All right so you're in class, those who
go to class, and you forgot to do the homework again.
8.44 -> So you turn to your classmate to ask for help and you realize you can't speak.
12.8 -> Your face is drooping.
15.3 -> You reach out in a panic and you find that you can't move your arm either.
18.72 -> So what's going on?
20.36 -> You're having a stroke.
22.64 -> So while you may be focused on
your arm or even your face
25.56 -> what's really going on is in your brain.
28.56 -> So what is a stroke exactly?
31.48 -> A stroke is a block often caused by a blood clot or a hemorrhage
35.62 -> which is a bleed of an artery within the brain.
38.72 -> It is currently ranked as the fifth leading cause of death and the leading cause of adult disability.
44 -> About 800,000 cases occur every year in the US alone.
48.48 -> And about 4 will occur just during my talk to you today.
51.72 -> The major issue with stroke is that you have your initial area of damage
55.66 -> but this begins to grow and expand in just a couple hours following your stroke, unless treated immediately.
62.02 -> Unfortunately there is only one treatment for stroke
65.14 -> and this is called Tissue Plasminogen Activator or TPA
68.7 -> which actually dissolves the blood clot causing the stroke.
71.98 -> But this unfortunately puts you at a risk for hemorrhage which is internal bleeding and most likely death
77.86 -> if used over four and a half hours after your stroke occurs.
81.74 -> But that sounds like plenty of time right like half of the lord of a rings movie. Yeah, yeah?
86.72 -> Yeah, unfortunately it's not.
88.84 -> So most patients don't actually come into the ER as soon as they start seeing symptoms.
93.34 -> But for the sake of this argument let's pretend that you do come into the ER
96.46 -> as soon as you realize you can't speak and you can't move your arm.
99.6 -> Now you have to be diagnosed as having a stroke with lengthy time-consuming tests
104.36 -> by the time you get out of these tests
you're most likely outside of this window
108.64 -> and because of this only 2 to 5
percent of patients are actually treated.
113.42 -> And this should terrify you.
115.46 -> So I actually plan to change this by looking at the blood and markers within the blood
120.24 -> to develop a timeline for stroke.
123.24 -> So I have analyzed 50,000 blood
markers from 0 to 6 hours after stroke occurs
129.8 -> and so far I have found 3 represented by BM 1, 2, and 3
134.22 -> that show unique patterns that could ideally be developed into a rapid blood test
139.54 -> similar to how a pregnancy test or a
urine test works
142.84 -> That could, you put some blood on one end of the essentially test strip
147.52 -> and it reads the levels of these blood markers
150.24 -> and tells you if you're having a stroke and how long it's been since your stroke occurred.
154.64 -> So in this case it's been two hours since you stroke occurred which is plenty of time for treatment.
159.04 -> If this could be represented and implemented within an ER
162.26 -> this could dramatically increase the amount of patients who are being treated in the first place
167.3 -> and hopefully save many lives.
169.48 -> Because, who knows, it may be someone you know.
171.74 -> It could be you.
173.14 -> So, thank you.
Source: https://www.youtube.com/watch?v=52WtGQfZyPw